15 Comments
Mar 6·edited Mar 6Liked by Heather Heying

This is timely, as the current bookclub selection on the Discord server is The Master and His Emissary by Iain McGilchrist, and one of the most surprising indications to me has been that the corpus callosum may be as inhibitory as it is useful for connectivity. The idea really blows my mind as I imagine the incredible continuous dance that occurs in our brains! It does appear that damage to the right hemisphere creates more practical problems for humans than similar damage to the left, and that the right has both more density and connectivity within it (just a couple of the multitude of curiosities that make up McGilchrist’s hypothesis for the right being the “Master”, and the left the highly capable “Emissary”!). So I guess when someone wants to claim that one is better than the other, the proper response is “better HOW?” or “for WHAT?”. But I do think one of my reasons for finding you and Bret so important to listen to is that you each have such powerful right hemisphere capabilities and are able to synthesize information so effectively, with humor and honest panache

Expand full comment

Allow me to speculate. All mammals dream (REM stage sleep) and we can still only guess why. I suffered a TBI in 1969, and the sleep disorders that accompanied that injury have given me some insights. I believe that short-term memory is electrochemical in nature. We are conscious (to a lesser extent than most of us believe) so that consciousness must have some components of spontaneity, while long-term memory is obviously something different. I think the purpose of REM sleep is to take the memories of the day and incorporate them into the purely chemical long-term memory. This seems to happen in the corpus calleosum. Brain injuries can cause epilepsy and many of my presentations seem like a very mild form epilepsy. "Micro-petit mal" is how I describe some of my states. It only makes sense that injury to the CC can lead to sleep disorders related to REM sleep if it is indeed part of that nightly process of memory incorporation.

Expand full comment
Mar 7·edited Mar 7

So far, so good, judging from our extravagant population explosion, assuming that's a useful metric. But that's usually been a challenge for a species. We are plunging headlong, cranium first ;-), into the scariest adaptive valley of our entire journey. Could be I'm a little biased on that point, not having been around for most of them, but it appears we may be encountering them at a highly accelerated rate of our own making.

Expand full comment

"The shape of a man’s corpus callosum tends to be different from that of a woman’s." It probably says more than I want to reveal about my own brain that I find myself more inclined to believe what you say, merely because you wrote "different from" rather than "different than."

Expand full comment

Hi Heather! Are you and Brett familiar with Dr. Matt Phillips? He started with degree in evolutionary biology and is now a neurologist doing clinical trials in Parkinsons, Alzheimers and brain cancer. I'm attaching a recent interview that explains his view on how this works. Fascinating stuff!

https://youtu.be/FT0NnWhfq1E?si=i7-88ebucWx5fBjO

Expand full comment

I believe (but its been years since I read it) that the real-life inspiration for the character of 'Rain Man' was actually a man that was born without a (or severely damaged?) corpus callosum. his last name was Mot; his mother was told when he was an infant, that he would not live to be a year old, yet I believe he lived into his 50's (he died about a decade ago). one of his many savant abilities, extreme speed reading, was attributed to his eyes operating independently, so that with a book opened in front of him, left eye read the page on the left and right eye read the page on the right, simultaneously and he retained it all.

although the movie 'Rain Man' is said to be about a person with autism, the character was the furthest thing from a typical individual with autism, imho. it gave people the false impression that all with the dx of 'autism' have some kind of a savant ability. when my son with autism was little (he'll be 20 this June), strangers would ask me what his 'super power' was. ('gee, I found him on top of the fridge last week so maybe climbing??' he had no natural concept of danger; NOT a good thing.) I haven't been asked that in many years, I believe because there are now so many severely disabled (poisoned!) kids & young adults around, most realize that Rain Man, Sheldon Cooper and The Good Doctor are extreme outliers that definitely don't represent any model for what 'autism' truly is.

Expand full comment

Would you write, sometime, about evolutionary missteps in humans?

Expand full comment